Respiratory Risk Report

Week ending in July 25, 2026

Biobot’s national wastewater network continues to show that SARS-CoV-2 is elevated across all four U.S. regions. The summer COVID-19 wave is here and growing.

The rest of the respiratory virus picture remains quiet. RSV, influenza A, influenza B, and HMPV are all circulating at very low levels, with activity either stable or declining.

Bottom line

COVID-19 transmission is rising across much of the country. It’s a good time to be a little more aware, especially if you’re traveling, heading to a crowded indoor event, or spending time with someone at higher risk of severe illness, including older adults, babies, pregnant people, and people who are immunocompromised.

The good news is that flu, RSV, and HMPV remain low.

---

National Outlook

COVID-19

Nationally, SARS-CoV-2 is increasing.

Influenza

Nationally, influenza A and B are holding steady at very low levels.

RSV

Nationally, RSV is holding steady at very low levels.

HMPV

Nationally, HMPV is decreasing.

---

Regional Outlook

The South

COVID-19: SARS-CoV-2 is increasing in the South.

Influenza: Influenza A and B are holding steady at very low levels in the South.

RSV: RSV is holding steady at very low levels in the South.

HMPV: HMPV is decreasing in the South.

The Midwest

COVID-19: SARS-CoV-2 is fluctuating in the Midwest.

Influenza: Influenza A and B are holding steady at very low levels in the Midwest.

RSV: RSV is holding steady at very low levels in the Midwest.

HMPV: HMPV is decreasing in the Midwest.

The Northeast

COVID-19: SARS-CoV-2 is fluctuating in the Northeast.

Influenza: Influenza A and B are holding steady at very low levels in the Northeast.

RSV: RSV is holding steady at very low levels in the Northeast.

HMPV: HMPV is decreasing in the Northeast.

The West

COVID-19: SARS-CoV-2 is increasing in the West.

Influenza: Influenza A and B are holding steady at very low levels in the West.

RSV: RSV is holding steady at very low levels in the West.

HMPV: HMPV is decreasing in the West.

---

You can subscribe to our Substack to get future updates delivered straight to your inbox.

---

Wastewater data from Biobot Analytics for RSV, influenza, HMPV, and SARS-CoV-2 are through July 25, 2026 (MMWR week 29).